Diagnostic Accuracy of Stereotactic Vacuum―assisted Biopsy of Breast Tissues

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  • Kawasaki Aika
    Kamakura Breast Cancer Center, Shonan Memorial Hospital
  • Tanaka Kanako
    Kamakura Breast Cancer Center, Shonan Memorial Hospital
  • Inoue Kenichi
    Kamakura Breast Cancer Center, Shonan Memorial Hospital
  • Goda Kyoko
    Kamakura Breast Cancer Center, Shonan Memorial Hospital
  • Sasaki Takeshi
    Department of Anatomical and Diagnostic Pathology, Graduate School of Medicine, The University of Tokyo
  • Doi Takako
    Kamakura Breast Cancer Center, Shonan Memorial Hospital

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  • ステレオガイド下吸引式乳房組織生検後の追跡調査による検査精度の検証

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Abstract

Stereotactic vacuum―assisted biopsy（Mammotome, ST―MMT）provides accurate diagnosis of breast cancer. Here we discuss the accuracy of the initial results we have obtained with the ST―MMT procedure in comparison with either re―biopsy or surgical resection. A total of２６４ST―MMT procedures conducted from February ２００９ through April ２０１３were reviewed retrospectively. Among the cases examined, １７２ were diagnosed as benign. During follow―up, six cases showed the change in the distribution of microcalcification, and re―biopsy was performed using ST―MMT. Although two of them were atypical papillary lesion or atypical ductal hyperplasia, none of the cases were diagnosed as breast cancer. In ２２ cases, atypical epithelium was found, and more careful follow―up was requested. Two years after initial biopsy, ductal carcinoma in situ was detected in one case. Seventy patients diagnosed as having malignant lesions underwent surgery at our hospital, and in ８７％ of them the ST―MMT result was found to be concordant with the final histology obtained at surgery. Nine cases that were diagnosed as ductal carcinoma in situ from the ST― MMT specimen were finally diagnosed as invasive carcinoma after surgery. ST―MMT is diagnostically reliable for microcalcifications in the breast. Although the procedure may be invasive, it is advantageous to patients in terms of safety and accuracy.

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