Computer Aided Detection of Mammographic Lesions Using Deep Learning

  • Inoue K
    Shonan Memorial Hospital, Breast Cancer Center
  • Kawasaki A
    Shonan Memorial Hospital, Breast Cancer Center
  • Koshimizu K
    Shonan Memorial Hospital, Breast Cancer Center
  • Yamanaka C
    Shonan Memorial Hospital, Breast Cancer Center
  • Doi T
    Shonan Memorial Hospital, Breast Cancer Center

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Other Title
  • ディープラーニングを用いたマンモグラフィの自動読影に関する初期検討
  • ディープラーニング オ モチイタ マンモグラフィ ノ ジドウドクエイ ニ カンスル ショキ ケントウ

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Abstract

Although the mammography screening system in Japan is managed by the Japan Central Organization on Quality Assurance of Breast Cancer Screening, system management varies regionally. The development of a novel screening method could improve system management, thereby increasing screening accuracy nationwide. The ”deep learning” approach to machine learning has recently been applied to many aspects of modern society. Here, we used a convolutional neural network(CNN)to evaluate the accuracy of mammography screening for the detection of breast cancer. A CNN with ten hidden layers, including convolutional layers and pooling layers, was programmed using the Python ver3.5 programming language and the Tensorflow library developed by Google. A total of 104 mammography images that had been diagnosed as depicting breast cancer were automatically divided into 20 image pieces, each with an image size of512x512 pixels. The CNN was then trained and tested using these 2046 images to evaluate the ability of the CNN to identify images containing breast cancer. The accuracy, sensitivity, specificity, positive prediction value, and negative prediction value were94.9%,88.5%, 97.1%, 91.1% and 96.1%, respectively, for the test data set. The deep learning approach to machine learning provided an excellent outcome in terms of the accuracy of detecting malignancies and is expected to contribute to the improvement and cost―effectiveness of mammography screening systems.

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