Biomacromolecular Neutron Crystallography

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Other Title
  • 生体分子の中性子単結晶回折（第三回）
  • 中性子生物(9)生体分子の中性子単結晶回折(第3回)タンパク質中性子結晶構造解析の実例と応用
  • チュウセイシ セイブツ(9)セイタイ ブンシ ノ チュウセイシタンケッショウ カイセツ(ダイ3カイ)タンパクシツ チュウセイシ ケッショウ コウゾウ カイセキ ノ ジツレイ ト オウヨウ
  • タンパク質中性子結晶構造解析の実例と応用
  • Practical Methods and Utilization of Neutron Crystallography for Understanding Protein Structure and Function

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Abstract

<p>Protein structure analysis using neutron diffraction (neutron protein crystallography; NPC) is gaining greater importance in the understanding of structure and function relationships of biological macromolecules such as proteins and DNA. Current developments of neutron diffractometers installed at the JAEA research reactor and pulsed neutron source permit observation of the locations of hydrogen atoms and hydrating water molecules and help understanding of important mechanisms of chemical reactions catalyzed by biological macromolecules. Here, we introduce practical approaches of NPC including sample preparation, crystal growth, structure determination and utilization of information obtained from NPC.</p>

Journal

  • hamon

    hamon 24 (1), 45-49, 2014

    The Japanese Society for Neutron Science

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