A Study on the Safety and Effectiveness of a Milky Lotion Containing Camellia Oil for Patients with Drying Dermatoses

ABE Namiko, KAWAKAMI Hiroshi, NISHIWAKI Kaoru, ARAI Takashi, TSUBOI Ryoji

doi:10.2336/nishinihonhifu.80.368

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乾燥性皮膚疾患患者に対するツバキ油配合乳液の安全性および有用性の検討
治療乾燥性皮膚疾患患者に対するツバキ油配合乳液の安全性および有用性の検討
チリョウカンソウセイヒフシッカンカンジャニタイスルツバキユハイゴウニュウエキノアンゼンセイオヨビユウヨウセイノケントウ

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Abstract

<p>A milky lotion containing camellia oil was administered to 46 patients with drying dermatoses including atopic dermatitis, asteatotic eczema, xeroderma, and senile pruritus for 4 weeks to examine its safety. The subjects were patients who regularly visited the Department of Dermatology at Tokyo Medical University Hospital, Ageo Central General Hospital, Todachuo General Hospital, or Niizashiki Central General Hospital during a 5-month period from November 2016 to March 2017. The results confirmed that the lotion was safe to use, since no side effects were observed. Evaluation of skin symptoms through observation by a physician indicated significant improvements in the scores of dryness and scratch marks between before and after the test (p < 0.01). In addition, the patient's subjective ratings of the moisture and itchiness of the skin were evaluated using a visual analogue scale. A significant increase in the moisture of the skin (p < 0.01) and a significant decrease in itchiness (p < 0.01) were observed between before and after the test. The subjects reported that the formulation spreads well without stickiness and has a good feeling upon use. Based on these results, we considered that this milky lotion containing camellia oil acts as a moisturizer that can be expected to reduce drying and itching and can be used safely for the daily skin care of patients with drying dermatoses.</p>

Journal

Nishi Nihon Hifuka

Nishi Nihon Hifuka 80 (4), 368-376, 2018-08-01

Western Division of Japanese Dermatological Association

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