Validity of a Self-administered Food Frequency Questionnaire for the Estimation of Acrylamide Intake in the Japanese Population: The JPHC FFQ Validation Study

  • Kotemori Ayaka
    Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center
  • Ishihara Junko
    Department of Food and Life Science, Azabu University
  • Nakadate Misako
    Division of Nutrition Science, Graduate School of Sagami Women’s University
  • Sawada Norie
    Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center
  • Iwasaki Motoki
    Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center
  • Sobue Tomotaka
    Department of Environmental Medicine and Population Sciences, Graduate School of Medicine, Osaka University
  • Tsugane Shoichiro
    Epidemiology and Prevention Group, Center for Public Health Sciences, National Cancer Center

書誌事項

公開日
2018-12-05
資源種別
journal article
DOI
  • 10.2188/jea.je20170186
公開者
日本疫学会

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説明

<p>Background: Acrylamide, a probable carcinogen to humans, forms during high temperature cooking. Dietary exposure to acrylamide among the Japanese population is unknown. We aimed to establish and validate a method to assess acrylamide exposure among the Japanese population using a food frequency questionnaire (FFQ) from the Japan Public Health Center-based prospective study.</p><p>Methods: Validation studies for the FFQ were conducted in 1994 (Cohort I, n = 215) and 1996 (Cohort II, n = 350). The 28-day dietary records (DRs) were collected over 1 year. The FFQ was distributed before and after DR collection. Data for acrylamide exposure were based on reported measurements in Japan, and calculations considered the cooking process for specific vegetables in a home setting. Spearman’s rank correlation and weighted kappa coefficients were calculated from energy-adjusted data.</p><p>Results: Mean acrylamide intake levels estimated from DRs for Cohorts I and II were 6.78 (standard deviation [SD], 3.89) µg/day and 7.25 (SD, 3.33) µg/day, and corresponding levels estimated from the FFQ were 7.03 (SD, 4.30) µg/day and 7.14 (SD, 3.38) µg/day, respectively. Deattenuated correlation coefficients for men and women were 0.54 and 0.48 in Cohort I and 0.40 and 0.37 in Cohort II, respectively. Weighted kappa coefficients were over 0.80 in all cases. The main contributing food groups from DRs were beverages, confectioneries, vegetables, potatoes and starches, and cereals.</p><p>Conclusions: High kappa values validate the use of FFQ in epidemiological studies. The marked contribution of cooked vegetables indicates the importance of considering household cooking methods in assessing acrylamide intake levels in the Japanese population.</p>

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