Biodegradable Neural Cell Culture Sheet Made of Polyanhydride thin Film with Micro-Trench Structures

DOI Web Site 参考文献30件
  • NAKAMURA Yuki
    Department of Precision Machinery Engineering, College of Science and Technology, Nihon University
  • IMAI Satomitsu
    Department of Precision Machinery Engineering, College of Science and Technology, Nihon University

書誌事項

公開日
2019-02-01
DOI
  • 10.1587/transele.2018oms0015
公開者
一般社団法人 電子情報通信学会

この論文をさがす

説明

<p>Technological developments in direction control of axonal outgrowth are a must for advances in regenerative medicine of the nervous system. In order to solve the problem, we fabricate a new neural cell culture sheet by applying the soft lithography technique to micro-patterning of the extracellular matrix and using thin-film biodegradable polymer for the scaffold. Micro-trenches were coated with Dulbecco's phosphate-buffered saline (-) containing laminin, using micro-molding in capillaries (MIMIC), a soft lithography technique. Biodegradable thin films with micro-trenches were fabricated by UV-curing a polyanhydride solution covering the negative SU-8 mold through thiol-ene polymerization. Both approaches were performed conveniently, rapidly, and accurately. It is thought that these techniques are excellent in terms of convenience and high speed, and can contribute greatly to regenerative medicine.</p>

収録刊行物

参考文献 (30)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ