ビスフォスフォネート製剤投与患者の壊死骨に放線菌が感染し下顎骨骨髄炎へと進展したと疑われた1例

DOI Web Site 参考文献15件
  • 竹内 惇平
    社会福祉法人恩賜財団済生会済生会兵庫県病院歯科口腔外科 神戸大学大学院医学研究科外科系講座口腔外科学分野
  • 尾古 俊哉
    社会福祉法人恩賜財団済生会済生会兵庫県病院歯科口腔外科
  • 古森 孝英
    神戸大学大学院医学研究科外科系講座口腔外科学分野

書誌事項

タイトル別名
  • A Case Where Osteonecrosis in a Patient, Who had been Administered Bisphosphonates, Progressed to Osteomyelitis of the Mandible due to Actinomycete Infection
公開日
2019
DOI
  • 10.15214/jsodom.32.16
公開者
日本口腔診断学会

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説明

Bisphosphonate-related osteonecrosis of the jaw is closely related to actinomycetes infection, and overseas reports have hypothesized that the occurrence of osteomyelitis is due to actinomycete infection in bisphosphonate-induced osteonecrosis.<br>We encountered a case where osteonecrosis in a patient, who had been administered bisphosphonates, progressed to osteomyelitis of the mandible due to actinomycete infection. Here we report this case and review the related literature. The patient underwent sequestrum removal and the wound was left open. After the surgery, the patient was administered AMPC 750mg/day for 2 months. Bone exposure was not observed 17 months after the surgery.

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