Influence of Gradual Loading on Disuse Atrophy of the Rat Soleus Muscle Depends on the Longitudinal Site
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- TANIGUCHI Hirotaka
- Department of Rehabilitation, Minamigaoka Hospital
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- ZUSHI Kazumi
- Department of Rehabilitation, Minamigaoka Hospital
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- YAMAZAKI Toshiaki
- Department of Physical Therapy, School of Health Science, Kanazawa University
Bibliographic Information
- Other Title
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- 廃用性萎縮に対する漸増荷重がラットヒラメ筋に与える影響
- 廃用性萎縮に対する漸増荷重がラットヒラメ筋に与える影響 : 長軸部位での検討
- ハイヨウセイ イシュク ニ タイスル ゼンゾウ カジュウ ガ ラットヒラメキン ニ アタエル エイキョウ : チョウジク ブイ デ ノ ケントウ
- ─長軸部位での検討─
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Description
<p>[Purpose] The purpose of this study was to verify the recovery after disuse atrophy by gradual loading. [Participants and Methods] Eight-week-old male Wistar rats were randomly assigned to control, hind-limb suspension (H), gradual loading after 7 days of hind-limb suspension (G), and constant loading after 7 days of hind-limb suspension (W) groups. At the end of the experimental period, the cross-sectional area and occurrence ratio of necrotic and central nuclear fibers were measured. [Results] The cross-sectional areas of the muscle fibers in the proximal region of the H and W groups were significantly smaller than those of the other groups, but there was no site-dependent difference in G group. [Conclusion] The results suggest gradual loading is an effective intervention for the proximal region which is the region most susceptible to disuse atrophy.</p>
Journal
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- Rigakuryoho Kagaku
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Rigakuryoho Kagaku 34 (1), 13-16, 2019
The Society of Physical Therapy Science
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Keywords
Details 詳細情報について
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- CRID
- 1390001288124287360
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- NII Article ID
- 130007604451
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- NII Book ID
- AN10472896
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- ISSN
- 24342807
- 13411667
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- NDL BIB ID
- 029530885
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed