Evaluation of the Prediction Equation for Spherical Equivalent Using Axial Length and Radius of Corneal Curvature in Three-year-old Children

  • Watanabe Ami
    Department of Ophthalmology, Fukushima Medical University
  • Mori Takafumi
    Department of Ophthalmology, Fukushima Medical University
  • Ayaka Kasai
    Department of Ophthalmology, Fukushima Medical University
  • Nitta Miwa
    Department of Ophthalmology, Fukushima Medical University
  • Saito Akiko
    Department of Ophthalmology, Fukushima Medical University
  • Hashimoto Teiko
    Department of Ophthalmology, Fukushima Medical University Sakuramizu Sakai Eye Clinic
  • Yago Keiko
    Fukushima Medical Center
  • Sekiryu Tetsuju
    Department of Ophthalmology, Fukushima Medical University

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  • 3歳児における眼軸長と角膜曲率半径による等価球面屈折値の予測式の検証

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Abstract

<p>[Purpose] We previously reported a prediction formula which predicts spherical equivalent (SE) under cycloplegia from axial length (AL) and corneal curvature radius (CCR) measured by a noncontact optical biometer. In this study, we examined the precision of the prediction formula in a different group of subjects and reported the results.</p><p>[Subjects and Methods] Subjects were 84 eyes of 42 3-year-old children who had received a cycloplegic refraction examination with 1% atropine eye drops twice a day for 7 days at the Fukushima Medical University Hospital after September 2014. AL and CCR were measured using an IOL Master® at the time of the cycloplegic refraction. With AL (x1) and the mean CCR (x2) of the steeper and flatter meridians, we estimated SE (ŷ) using a previously reported prediction formula (ŷ =967.37/x1-287.99/x2-4.78) and compared the estimated values to the actual measurements (y) obtained at the cycloplegic refraction. </p><p>[Results] The values of x1, x2, and y ranged from 19.41 to 23.03 mm, 7.17 to 8.18 mm, and -1.62 to +10.38 D, respectively. The actual SE measurement (mean±standard deviation) was +2.89±2.40 D and the predicted SE was +3.12±1.98 D. A strong correlation was observed between the actual and predicted values (r = 0.97, P < 0.001). Of 84, 42 (50%) eyes had a difference of < 0.5 D between the predicted and actual values and 73 (87%) eyes had a difference of < 1.0 D. The maximum difference was 2.16 D. </p><p>[Conclusions] The predicted SE values obtained by the IOL Master® showed a strong correlation with the actual measurements with 50% of the subjects showing a measurement error of < 0.5 D. This suggests that this method may be useful for children who can not use atropine ophthalmic solution for reasons such as systemic diseases.</p>

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