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Rhinosinusitis Caused by Aspergillus oryzae: A Case Report

  • Yamauchi Tomohiko
    Department of Otolaryngology Head and Neck Surgery, Jichi Medical University
  • Yokoyama Shuji
    Department of Otolaryngology, Fukushima Medical University Aizu Medical Center
  • Ogawa Hiroshi
    Department of Otolaryngology, Fukushima Medical University Aizu Medical Center

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Other Title
  • <i>Aspergillus oryzae</i>による鼻副鼻腔炎例

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Abstract

<p>A 51-year-old male who worked as a brewer of miso (fermented soybean paste) presented with a chief complaint of vertigo and was diagnosed with perilymphatic fistula. Head computed tomography (CT) revealed no significant findings in the cerebellum and brainstem, but there was soft tissue density with calcification in the right maxillary sinus. Although there were no nasal symptoms, non-invasive chronic fungal rhinosinusitis was suspected. After resolution of the perilymphatic fistula, endoscopic sinus surgery (ESS) was performed. The pathology of the specimen from the right maxillary sinus revealed only crystal deposition, but the fungus was not identified. Thirteen months after ESS, the patient visited our hospital again with a complaint of pain in the right cheek and rhinorrhea. Endoscopy revealed hyphae in the right nasal cavity. A culture of white pus from the right maxillary sinus revealed Aspergillus, not otherwise specified. Polymerase chain reaction (PCR) of the culture product was positive for Aspergillus oryzae, and this was considered to be the causative organism of rhinosinusitis.</p>

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