Enzootic bovine leucosis in a Holstein cow without lymphadenopathy or pelvic masses

  • Sakaguchi K.
    Department of Clinical Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
  • Maezawa M.
    Department of Clinical Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
  • Tanaka Y.
    Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
  • Tagaino Y.
    Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
  • Uwasawa A.
    Tokachi Agricultural Mutation Aid Association
  • Watanabe K.
    Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
  • Horiuchi N.
    Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
  • Kobayashi Y.
    Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine
  • Inokuma H.
    Department of Clinical Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine

Bibliographic Information

Other Title
  • 体表リンパ節腫大と骨盤腔内腫瘤の認められない地方病性牛白血病ホルスタイン種乳牛の1 症例
  • 症例報告 体表リンパ節腫大と骨盤腔内腫瘤の認められない地方病性牛白血病ホルスタイン種乳牛の1症例
  • ショウレイ ホウコク タイヒョウ リンパセツ シュダイ ト コツバン コウナイ シュリュウ ノ ミトメラレナイ チホウビョウセイギュウ ハッケツビョウ ホルスタインシュ ニュウギュウ ノ 1 ショウレイ

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Abstract

<p> A 51-month-old Holstein cow was presented for anorexia(Day 1). Jugular vein distension and auscultation difficulty were noted on examination, and pericarditis was suspected. Lymphadenopathy was not detected by both surface and rectal palpations. Hematological examination revealed marked lymphocytosis(80,436/μℓ)with atypical lymphocytes. An ELISA test for bovine leukemia virus antibody was positive. Increased activities of total LDH and LDH isozymes 2 and 3 were 15,640, 3,909 and 3,128 U/l, respectively. Serum thymidine kinase activity was also remarkably increased to 1,920U/l. On Day 10, the patient showed brisket edema and dyspnea and died. At necropsy, multiple masses were found in the pericardial cavity with bloody pericardial fluid. Several masses were also detected in the anterior mediastinum, around the gall bladder and pancreas, in the mesenteric, and around the abomasum. Histopathological analysis revealed that the masses were B-cell lymphoma which led to a diagnosis of enzootic bovine leucosis.</p>

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