A Case of Oropharyngeal Squamous Cell Carcinoma Complicated by Multiple Cerebral Infarctions due to Trousseau Syndrome
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- Yamazaki Ayame
- Tokyo Metropolitan Health and Hospitals Corporation, Ohkubo Hospital
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- Tanabe Ayumi
- Tokyo Women’s Medical University
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- Mukai Masaaki
- Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital
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- Shirakura Satoshi
- Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital
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- Sugimoto Taro
- Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital
Bibliographic Information
- Other Title
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- Trousseau症候群により多発脳梗塞を合併した中咽頭扁平上皮癌例
- 臨床 Trousseau症候群により多発脳梗塞を合併した中咽頭扁平上皮癌例
- リンショウ Trousseau ショウコウグン ニ ヨリ タハツ ノウコウソク オ ガッペイ シタ チュウ イントウ ヘンペイ ジョウヒ ガン レイ
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Abstract
<p>Trousseau syndrome refers to a hypercoagulable state associated with malignancies. It is characterized by venous, and more rarely, arterial thrombosis. The most common pathology encountered in cases with arterial thrombosis is cerebral infarction, which is often multiple and diffusely distributed. Trousseau syndrome is commonly reported in cases of adenocarcinoma and is relatively rare in cases of squamous cell carcinoma. We report a rare case of multiple cerebral infarcts due to Trousseau syndrome in a patient with oropharyngeal squamous cell carcinoma.</p><p>A 61-year-old patient who had been treated for Stage IVB oropharyngeal carcinoma presented to our emergency department with double vision, nausea and difficulty in walking. Clinical examination revealed upbeat nystagmus and, raised D-dimer levels, and MRI showed multiple bilateral cerebral infarcts. Anticoagulant treatment was commenced, but the patient died one month after detection of the cerebral infarctions due to disease progression.</p><p>When encountering patients with multiple infarctions or recurrent thrombotic episodes, it is important to suspect Trousseau syndrome, and to carry out investigation to detect the responsible occult carcinomas and promptly commence treatment.</p>
Journal
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- Practica Oto-Rhino-Laryngologica
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Practica Oto-Rhino-Laryngologica 112 (4), 263-267, 2019
The Society of Practical Otolaryngology
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Details 詳細情報について
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- CRID
- 1390001288141337088
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- NII Article ID
- 130007621744
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- NII Book ID
- AN00107089
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- ISSN
- 18844545
- 00326313
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- NDL BIB ID
- 029656537
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed