Successful Treatment of Acute Chest Syndrome with Manual Exchange Transfusion in a Patient with Sickle Beta<sup>+</sup>-thalassemia

  • Kawahara Akihiro
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Morioka Takehiko
    Department of Hematology, Hiroshima University Hospital, Japan
  • Otani Yuichiro
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Kanno Keishi
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Edahiro Taro
    Department of Hematology, Hiroshima University Hospital, Japan
  • Fukushima Noriyasu
    Department of Hematology, Hiroshima University Hospital, Japan Department of Hematology and Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Japan
  • Nagasaka Sachi
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Housai Mika
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Kakimoto Masaki
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Tsuji Naoki
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Asano Shuntaro
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Kikuchi Yuka
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Kobayashi Tomoki
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Miyamori Daisuke
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Ishida Ryoko
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Kimura Kazuki
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Kishikawa Nobusuke
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Mizooka Masafumi
    Department of General Internal Medicine, Hiroshima University Hospital, Japan
  • Ichinohe Tatsuo
    Department of Hematology, Hiroshima University Hospital, Japan Department of Hematology and Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Japan
  • Tazuma Susumu
    Department of General Internal Medicine, Hiroshima University Hospital, Japan

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説明

<p>Acute chest syndrome (ACS), characterized by fever, respiratory symptoms, and new pulmonary infiltration, is a serious complication of sickle cell disease (SCD). Regardless of the etiology, the conventional treatment options for ACS include empirical antibiotic therapy, the administration of analgesics, and red cell transfusion. The indications and methods of red cell transfusion are critical. We herein report the case of a 26-year-old African-American man with SCD who developed ACS and who was successfully treated with manual exchange transfusion. Despite increasing globalization, SCD remains extremely rare in Japan. Manual exchange transfusion can be performed easily anywhere and should be considered for treating SCD patients presenting with ACS. </p>

収録刊行物

  • Internal Medicine

    Internal Medicine 58 (11), 1629-1634, 2019-06-01

    一般社団法人 日本内科学会

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