Characteristic features of newly established specific pathogen-free albino large rabbit (JW-AKT): Comparison with Japanese White and New Zealand White rabbits

  • MATSUDA Yukihisa
    Animal Research Laboratory, Bioscience Education-Research Support Center, Akita University, 1-1-1 Hondo, Akita 010-8543 Japan
  • SHIBATA Yoshiko
    Animal Research Laboratory, Bioscience Education-Research Support Center, Akita University, 1-1-1 Hondo, Akita 010-8543 Japan
  • BASAKI Keita
    Animal Research Laboratory, Bioscience Education-Research Support Center, Akita University, 1-1-1 Hondo, Akita 010-8543 Japan
  • FUKUDA Yasuyoshi
    Animal Research Laboratory, Bioscience Education-Research Support Center, Akita University, 1-1-1 Hondo, Akita 010-8543 Japan
  • TAKAKI Naofumi
    Kitayama Labes Co., Ltd., 8046-1 Nishiminowa, Ina, Nagano 399-4501 Japan
  • MAEDA Tatsuhiro
    Kitayama Labes Co., Ltd., 8046-1 Nishiminowa, Ina, Nagano 399-4501 Japan
  • HIRAO Masao
    Kitayama Labes Co., Ltd., 8046-1 Nishiminowa, Ina, Nagano 399-4501 Japan
  • YANO Megumi
    Animal Research Laboratory, Bioscience Education-Research Support Center, Akita University, 1-1-1 Hondo, Akita 010-8543 Japan
  • HIGASHIYA Misako
    Animal Research Laboratory, Bioscience Education-Research Support Center, Akita University, 1-1-1 Hondo, Akita 010-8543 Japan
  • OBATA Takahiro
    Animal Research Laboratory, Bioscience Education-Research Support Center, Akita University, 1-1-1 Hondo, Akita 010-8543 Japan
  • SEKI Shinsuke
    Animal Research Laboratory, Bioscience Education-Research Support Center, Akita University, 1-1-1 Hondo, Akita 010-8543 Japan
  • NISHIJIMA Kazutoshi
    Animal Research Laboratory, Bioscience Education-Research Support Center, Akita University, 1-1-1 Hondo, Akita 010-8543 Japan

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<p>The present study was conducted to reveal characteristic features of albino large rabbit (JW-AKT) which we formerly established a specific pathogen-free (SPF) colony. Body weights of JW-AKT rabbit at 52 weeks old was 5.7 ± 0.4 kg in males and 6.4 ± 0.4 kg in females. Weight of body, heart, lung and kidney in JW-AKT rabbit was significantly higher than in Japanese white and New Zealand white rabbits in both sexes. Though the body weight (BW) was rather lower in males, body length and brain weights tended to be higher in males than in females. Since body fat was significantly higher in females, what affects difference in BW is body fat, rather than the physical constitution of female JW-AKT rabbit. No critical sex difference was found in hematological parameters in JW-AKT rabbit. The results indicated that JW-AKT were about 1.5 times larger than the general laboratory rabbits with common properties in hematology. Thus, JW-AKT rabbit could be used as a novel SPF experimental animal model with some advantages in surgical experiments or collection of large amount of biological specimen.</p>

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