Two elderly cases of gallstone pancreatitis associated with administration of the ceftriaxone (CTRX)

DOI
  • Saito Michihiro
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University, Ohashi Medical Center
  • Shigoka Hiroaki
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University, Ohashi Medical Center
  • Gon Katsushige
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University, Ohashi Medical Center
  • Tanaka Takashi
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University, Ohashi Medical Center
  • Saito Kota
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University, Ohashi Medical Center
  • Maetani Iruru
    Division of Gastroenterology and Hepatology, Department of Internal Medicine, Toho University, Ohashi Medical Center

Bibliographic Information

Other Title
  • セフトリアキソン（CTRX）投与が原因と考えられる胆石性膵炎を発症した高齢者の2例

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Description

<p>Pseudolithiasis after administration of ceftriaxone (CTRX) is widely known, and mainly reported in children. While, in recent years, reports in elderly are increasing. We report two elderly cases of gallstone pancreatitis associated with administration of the CTRX. Before the onset of gallstone pancreatitis, the first case 80-year-old female was given CTRX for 3 days because of bronchialitis. The second case 70-year-old male was given CTRX for 5 days because of colitis. Both cases were admitted to the hospital and started receiving conservative treatment. However, elevation of inflammation and hepatobiliary enzymes were exacerbated, then they required endoscopic treatment. Most of CTRX-associated pseudolithiasis are asymptomatic, and disapear early due to discontinuation of administration. Therefore, even if symptoms such as abdominal pain appear, conservative treatment is the first choice. However, we are necessary to be fully aware of the possibility that endoscopic procedures required as in our cases and CTRX-associated pseudolithiasis is easily formed not only in children but also in elderly.</p>

Journal

  • Tando

    Tando 33 (5), 862-870, 2019-12-31

    Japan Biliary Association

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