Evaluating accuracy of the gastric cancer risk assessment using hybrid ABC in gastric cancer screening

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  • ハイブリッドABCを用いた胃がんリスク層別化の胃がん検診における有用性評価

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<p>Aims: Evaluating the accuracy of hybrid ABC (Hyb ABC) combined with the serum ABC classification and the endoscopic ABC classification in gastric cancer risk assessment</p><p>Methods: A total of 462 patients were enrolled in the study. All persons underwent endoscopic examination and several H. pylori tests at the Inui Clinic of Internal Medicine, between May 2016 and January 2018. They were stratified into five groups (A to E) based on serum ABC classification using L-type Wako H. pylori antibody J. Furthermore, they were stratified into five groups (A to E) based on the grades of endoscopic findings (endoscopic ABC classification). Hyb ABC was defined as consistent results of serum ABC classification and endoscopic ABC classification.</p><p>Results: Hyb A had 100% accuracy at diagnosing naïve H. pylori-infected status. The accuracy of Hyb B and Hyb C at diagnosing current H. pylori-infected status were 96.4% and 94.4%, respectively. The accuracy of both Hyb D and Hyb E at diagnosing previous H. pylori-infected status was 100%.</p><p>Conclusion: This study showed that the hybrid ABC enables to accurate gastric cancer risk assessment reflected by H. pylori-infected status.</p>

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