A Case of Cecal Ulcer Hemorrhage in a Hemodialysis Patient Taking Sodium Polystyrene Sulfonate

Bibliographic Information

Other Title
  • ポリスチレンスルホン酸ナトリウム内服中の透析患者に発症した盲腸潰瘍出血の1例

Search this article

Abstract

<p>A 41-year-old man complained of right lower abdominal pain, vomiting and diarrhea. He was suffering chronic renal failure with Alport syndrome and had been treated with hemodialysis and sodium polystyrene sulfonate(Kayexalate, SPS) from 25 years previously. Abdominal computed tomography suggested ascending colon diverticulitis. Conservative treatment with antibiotics improved the abdominal pain and inflammatory response. However, a massive hemorrhagic stool (1,600g) was observed after hemodialysis on the 11th day. Since colonoscopic hemostasis was difficult due to massive hemorrhage in the right side colon, a right hemicolectomy was performed and an ileostomy with a transverse mucous fistula was carried out on the 15th day. Pathological examination revealed a 30mm, poorly defined ulcer in the cecum, accompanied with crystalline material, suggesting an SPS related ulcer. Although commonly used for improving hyperkalemia in patients with chronic renal failure, SPS may sometimes induce severe intestinal injury.</p>

Journal

Citations (1)*help

See more

Details 詳細情報について

Report a problem

Back to top