Preoperative Instrumental Activities of Daily Living Predicts Survival After Transcatheter Aortic Valve Implantation
-
- Fukui Shogo
- Department of Rehabilitation Medicine, Keio University School of Medicine Graduate School of Health Management, Keio University
-
- Kawakami Michiyuki
- Department of Rehabilitation Medicine, Keio University School of Medicine
-
- Otaka Yohei
- Department of Rehabilitation Medicine I, School of Medicine, Fujita Health University
-
- Ishikawa Aiko
- Department of Rehabilitation Medicine, Keio University School of Medicine
-
- Yashima Fumiaki
- Department of Cardiology, Keio University School of Medicine
-
- Hayashida Kentaro
- Department of Cardiology, Keio University School of Medicine
-
- Oguma Yuko
- Graduate School of Health Management, Keio University Sports Medicine Research Center, Keio University
-
- Fukuda Keiichi
- Department of Cardiology, Keio University School of Medicine
-
- Liu Meigen
- Department of Rehabilitation Medicine, Keio University School of Medicine
説明
<p>Background:This aim of this study was to clarify prognosis after transcatheter aortic valve implantation (TAVI) in patients with aortic stenosis (AS) and to identify baseline factors associated with mortality.</p><p>Methods and Results:We prospectively enrolled 257 consecutive elderly persons with AS who were referred to Keio University Hospital and who underwent assessment of cardiac, physical (walking speed), cognitive, and renal functions, nutritional status, activities of daily living (ADL), instrumental ADL (IADL) assessed with the Frenchay activities index (FAI), and comorbidities. The primary outcome was postoperative death. Differences in basic characteristics were compared between a group that survived for a median of 661 days (IQR, 0–1,289 days) after TAVI and a group that did not. Multivariate hazard ratios (HR) were calculated for independent factors selected in Cox proportional hazard models. Thirty-one individuals died during follow-up. Walking speed was significantly faster (0.87±0.25 vs. 0.70±0.24 m/s, P<0.001) and FAI was significantly higher (21.2±8.0 vs. 15.7±8.0, P=0.026) in the survival group compared with those who died. Multivariate HR for mortality according to walking speed was 0.05 (95% CI: 0.028–0.091) in model 1 and 0.04 (95% CI: 0.020–0.081) in model 2, and those for FAI were 0.94 (95% CI: 0.92–0.95) and 0.92 (95% CI: 0.90–0.92), respectively.</p><p>Conclusions:Preoperative walking speed and IADL are crucial factors associated with prognosis after TAVI even after adjustment.</p>
収録刊行物
-
- Circulation Reports
-
Circulation Reports 2 (2), 83-88, 2020-02-10
一般社団法人 日本循環器学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390002184873601536
-
- NII論文ID
- 130007796335
-
- ISSN
- 24340790
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可