Indeterminate Cases of Thyroid Fine-Needle Aspiration Cytology

  • Yamada Koichiro
    Department of Otolaryngology, Japanese Red Cross Wakayama Medical Center
  • Takebayashi Shinji
    Department of Otolaryngology-Head & Neck Surgery, Kobe City Medical Center General Hospital
  • Honda Keigo
    Department of Otolaryngology, Japanese Red Cross Wakayama Medical Center
  • Kimura Toshiya
    Department of Otolaryngology, Japanese Red Cross Wakayama Medical Center
  • Miura Makoto
    Department of Otolaryngology, Japanese Red Cross Wakayama Medical Center

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Other Title
  • 穿刺吸引細胞診にて鑑別困難であった甲状腺腫瘍の検討
  • センシ キュウイン サイボウシン ニテ カンベツ コンナン デ アッタ コウジョウセン シュヨウ ノ ケントウ

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Abstract

<p>We retrospectively reviewed 149 patients who underwent fine-needle aspiration for thyroid tumor between November 2012 and August 2015 at Japanese Red Cross Wakayama Medical Center and were found to have indeterminate cytology.</p><p>Sixty-eight patients (45.6%) underwent surgery; of those, the tumors of 29 patients (42.6%) were diagnosed as malignant. The most frequent type of malignancy was papillary thyroid carcinoma, while that of benign cases was adenomatous goiter, followed by follicular adenoma. Eighty patients underwent a repeat FNA. Repeat FNA results of malignancy or suspected malignancy were found in 7 patients. All 7 patients underwent surgery and 6 patients were found to have malignant post-operative pathology. Repeat FNA results were benign in 35 patients. Seven of those had surgery and 3 patients were found to have malignant post-operative pathology.</p><p>Overall, 45.6% underwent surgery, and the post-operative pathology malignancy rate was 42.6%. Even if repeat FNA results are benign, the possibility of malignancy cannot be ruled out completely. It is important to have careful observation for patients with indeterminate thyroid tumors, even if surgery is not performed.</p>

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