ケロイドの病態と治療

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  • 土佐 眞美子
    日本医科大学付属病院形成外科・再建外科・美容外科
  • 小川 令
    日本医科大学付属病院形成外科・再建外科・美容外科

書誌事項

タイトル別名
  • Pathogenesis and Treatment of Keloids
  • ケロイド ノ ビョウタイ ト チリョウ

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抄録

<p>Keloids are chronic inflammatory fibrous tumors that cause excessive production of such extracellular macromolecules as collagen, due to the overexpression of various growth factors and cytokines. The etiology of keloids is unknown. They cause pain and itching, which together with the red mass leads to physical and mental stress in patients. No definitive treatment for keloids has been established, although various treatment methods have been reported, and the current consensus is that the recurrence of keloids cannot be completely suppressed. Elucidation is awaited of the pathologic mechanism of keloid development and identification of signal transduction pathways that will help establish a molecular targeted therapy for keloids.</p>

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