Relationship between wave-like structure and muscle fiber type in immobilized mouse soleus muscle

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  • Sakamoto Miki
    Faculty of Rehabilitation, School of Allied Health Sciences, Kitasato University
  • Harada Takashi
    Department of Physical Medicine and Rehabilitation, Toho University School of Medicine
  • Futami Toshiro
    Faculty of Rehabilitation, School of Allied Health Sciences, Kitasato University
  • Muro Masuo
    Exercise Physiology Laboratory, Toho University School of Medicine
  • Oka Kazuyuki
    Department of Biology, Toho University School of Medicine

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<p>  Immobilized soleus muscles reportedly forms a degeneration structure called a wave-like structure. The wave-like structure offers a sensitive marker of morphological change induced by disuse. We examined the frequency of wave-like structures induced by immobilization for type I and type II muscle fibers. For each duration of immobilization, frequencies of wave-like structures were higher for type II fibers than for type I fibers (P<0.01).</p><p>  Distributions of fiber types in mouse soleus muscles were also investigated using routine ATPase methods. No deviations in distribution were observed and numbers of each fiber type were almost equal in each soleus muscle.</p>

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