<p>INTRODUCTION: Alfred NOBEL destined 1895 prices for physics, chemistry, domain of physiology or medicine. Physiology is mother of many life sciences (M. VISSCHER/USA: Plenary lecture IUPS New Delhi, Proc. X-13, 1974). Pharmacology considers influence of drugs on pathophysiological reactions (related also to morphological & genetic factors). In 2009 was 50 years of foundation of IUPHAR (1959-2009), independently from IUPS. Pharmacology & toxicology have a central position in experimental & clinical medicine: Future needs new ideas supporting higher efficacy of education & research on this fundamental science.</p><p>CONCEPTION: During International Congress for Physiology (IUPS-2017 Rio de Janeiro) is given report about: On philosophical physiology (PHP), which could be applied in pharmacology & toxicology, considering philosophical fundamentals.</p><p>A. EPISTEMOLOGY. Practical example for an integrative pharmaco-toxicology is given in this congress: Michailov, Neu et al. (IUPHAR-2018) and long-term systematic reports to all congresses before (from 2014-Cape-Town upto 1975-Helsinki) conc. influence of drugs/toxicants on cardio-vascular and urogenital systems, also in radio-oncology.</p><p>B. MORAL PHILOSOPHY. Independently from various modern ethical theories (deontology, etc.) has to be considered Kants human obligations to himself (pharmacologist-toxicologist&personnel), other humans (patients using drugs or are influenced by xenobiotics), sub-human, e.g. reduction of animal experiments, suprahuman beings: adjuvant psychotherapy to pharmaco-therapy, practices from Brahmanism-Yoga, Buddhism-Zen, etc.</p><p>C. AESTHETICS. In relation to A.-B. is necessary to destine limits & volume of pharmacotherapy and radiochemotherapy (primum non nocere), also adjuvant treatment, e.g. by music therapy, meditation, etc.</p><p>CONCLUSION: Establishment of regular common congress-sessions of IUPHAR-IUTOX-continental-national societies in context of A.-C. with philosophical (FISP-ISB-EACME, etc.), psychological (IUPsyS, etc.), biological (ISB, etc.), medical societies (ISIM-ICC-FIGO-SIU) could open new scientific & political dimension in pharmaco-toxicology, leading to humanization, higher efficacy of medicine supporting UNO-Agenda21 for better health, education, ecology, economy on global level.</p><p>Dedication see-Michailov-Neu-et-al.</p><p>References: 1. IUPHAR Int.Congr.Proc.: 2014-Cape-Town Basic&Clin.Pharm.&Tox.(BCPT), Vol.115/s1, p.77-78/312-313; 2010-Copenhagen Basic&Clin.Pharm.&Tox. 17/S1,454-5/488-9; 2006-Beijing Acta-Pharm.Sinica S1,178/411; 2002-San-Francisco Pharmacologist 44/251,26.8; 1998-Muenchen Arch.Pharmacol. 358/1/1,R276/R255; 1994-Montreal Can.J.Physiol.Pharmacol. 72/S1,164/164; 1990-Amsterdam Eur.J.Pharmacol. 183/4,1537-1538; 1987-Sydney P1018/P500; 1984-London 1672P/412P; 1981-Tokyo 1530/1880; 1978-Paris 36/2175&2680; 1975-Helsinki 435.</p><p>2. IUPS-CongrProc (IntUnPhysiolSci) 2017-Rio-de-Janeiro Abs.-Book No. 977/999/1001/1003; 2009-Kyoto/XXII:JPhysiolSci 59/S1:168&214&447-8; 1974-New-Delhi/Proc.XI+XII:273&378&1133.</p><p>3. FISP-2013-Athens (World-Congr.Philos.) Proc464-5&503-4,766; 2008-Seoul, Abstr.Book 338-9,363-5, DVD-2010, Vol. 4:101-8, 20:203-14, 45:229-237, 37:195-202.</p>