A Case of a Patient Diagnosed with Trisomy 13 Who Required Treatment for Pneumonia after Cheiloplasty

DOI
  • NAKAZONO Kenta
    Department of Oral and Maxillofacial Surgery, Field of Oral and Maxillofacial Rehabilitation, Advanced Therapeutic Course, Kagoshima University Graduate School of Medical and Dental Sciences
  • ISHIHATA Kiyohide
    Department of Oral and Maxillofacial Surgery, Field of Oral and Maxillofacial Rehabilitation, Advanced Therapeutic Course, Kagoshima University Graduate School of Medical and Dental Sciences
  • KIBE Toshiro
    Department of Oral and Maxillofacial Surgery, Field of Oral and Maxillofacial Rehabilitation, Advanced Therapeutic Course, Kagoshima University Graduate School of Medical and Dental Sciences
  • TEZUKA Masahiro
    Department of Oral and Maxillofacial Surgery, Field of Oral and Maxillofacial Rehabilitation, Advanced Therapeutic Course, Kagoshima University Graduate School of Medical and Dental Sciences
  • FUCHIGAMI Takao
    Department of Oral and Maxillofacial Surgery, Field of Oral and Maxillofacial Rehabilitation, Advanced Therapeutic Course, Kagoshima University Graduate School of Medical and Dental Sciences
  • NAKAMURA Norifumi
    Department of Oral and Maxillofacial Surgery, Field of Oral and Maxillofacial Rehabilitation, Advanced Therapeutic Course, Kagoshima University Graduate School of Medical and Dental Sciences

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Other Title
  • 口唇形成術後に肺炎加療を要した13トリソミー患児の一例

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Description

Trisomy 13 is a chromosomal disorder with systemic malformations reported by Patau in 1960. The prognosis is markedly poor, and 90％ of affected infants do not survive beyond the first year of life. Treatment strategies for patients with chromosomal abnormalities, such as trisomy 13, vary among facilities, and no consensus has been reached. We describe the case of a patient with trisomy 13 and bilateral cleft lip and palate who underwent cheiloplasty and required postoperative treatment for pneumonia. A 2-year-old girl underwent cheiloplasty using a modified Manchester’s technique under general anesthesia. She had already received a tracheostomy at the age of 1 year and 2 months, and so the intraoperative respiratory management was performed through the tracheostomy tube. The operation was completed without large fluctuation in her general condition and postoperative management was performed in the ICU. However, on the third postoperative day, she developed severe pneumonia. In cooperation with pediatricians, ventilator management and carbapenem antibiotics and immunoglobulin preparations were administered, her general condition improved, and she was discharged on the 14th postoperative day. At 1 year and 6 months since the cheiloplasty, her general condition is relatively stable and the surgical scar is not conspicuous.

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