Retroperitoneal hemorrhage of adrenal metastasis from hepatocellular carcinoma during lenvatinib treatment
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- Saito Naoto
- Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital
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- Hatanaka Takeshi
- Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital
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- Nakano Yuya
- Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital
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- Yoshida Sachiko
- Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital
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- Hachisu Yoko
- Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital
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- Tanaka Yoshiki
- Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital
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- Yoshinaga Teruo
- Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital
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- Kubota Jun
- Department of Radiology, Gunma Saiseikai Maebashi Hospital
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- Tokue Hiroyuki
- Department of Diagnostic and Interventional Radiology, Gunma University Graduate School of Medicine
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- Shibuya Kei
- Department of Radiology, Gunma University Graduate School of Medicine
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- Tojima Hiroki
- Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine
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- Sato Ken
- Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine
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- Uraoka Toshio
- Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine
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- Kakizaki Satoru
- Department of Gastroenterology and Hepatology, Gunma University Graduate School of Medicine
Bibliographic Information
- Other Title
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- レンバチニブ治療中に腫瘍内出血を経て後腹膜出血をきたした肝細胞癌右副腎転移の一例
- 症例報告 レンバチニブ治療中に腫瘍内出血を経て後腹膜出血をきたした肝細胞癌右副腎転移の一例
- ショウレイ ホウコク レンバチニブ チリョウ チュウ ニ シュヨウ ナイシュッケツ オ ヘテ アトバラマク シュッケツ オ キタシタ カン サイボウ ガン ミギ フクジン テンイ ノ イチレイ
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Abstract
<p>A 72-year-old woman with lung metastases and right adrenal metastasis from hepatocellular carcinoma was treated with lenvatinib. Progressive disease was observed on computed tomography (CT) 12 weeks after the initial treatment with lenvatinib. Two days later, she complained of a sudden onset of right upper quadrant pain; the CT showed retroperitoneal hemorrhage due to right adrenal metastasis. Emergent angiography displayed the extravasation and transcatheter arterial embolization (TAE) was performed from the right inferior phrenic artery. The patient's abdominal pain improved gradually, and she was discharged 18 days after TAE. We retrospectively reviewed the CT findings 12 weeks following the initial treatment with lenvatinib, showing that an area of high attenuation was apparent on the caudal side of the tumor, suggesting intratumoral hemorrhage. The close screening for presence of intratumoral hemorrhage was required during lenvatinib treatment.</p>
Journal
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- Kanzo
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Kanzo 61 (11), 588-596, 2020-11-01
The Japan Society of Hepatology
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Keywords
Details 詳細情報について
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- CRID
- 1390004951538647168
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- NII Article ID
- 130007937417
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- NII Book ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- NDL BIB ID
- 030731669
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed