Two Cases of Widespread Contact Dermatitis to OTC Medicaments

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  • HIRAI Yuka
    Department of Dermatology, Showa University Fujigaoka Hospital
  • TAKEI Hanako
    Department of Dermatology, Showa University Fujigaoka Hospital
  • KASA Yurina
    Department of Dermatology, Showa University Fujigaoka Hospital
  • ITOH Yuta
    Department of Dermatology, Showa University Fujigaoka Hospital
  • OHTOSHI Shinpei
    Department of Dermatology, Showa University Fujigaoka Hospital
  • NAKADA Tokio
    Department of Dermatology, Showa University Fujigaoka Hospital

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Other Title
  • 広範囲に皮疹を認めたOTC医薬品による接触皮膚炎の２例
  • 症例 広範囲に皮疹を認めたOTC医薬品による接触皮膚炎の2例
  • ショウレイ コウハンイ ニ ヒシン オ ミトメタ OTC イヤクヒン ニ ヨル セッショク ヒフエン ノ 2レイ

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Abstract

<p>　We report two cases of widespread contact dermatitis caused by over-the-counter (OTC) medicaments. Case 1 : A male in his 50s developed itching on the legs and feet one month prior to presentation. Although he applied an antipruritic OTC medicament, MUHI®S2a, for 2 weeks and MUHIα®EX for the following 2 weeks, lesions enlarged and increased in number on the face and trunk. Physical examination revealed edematous erythema and papules on the face, scattered papules on the trunk and extremities, and erythematous lesions on the lower thighs and dorsum feet. Patch testing resulted in a positive reaction to MUHIα®EX. This patient was diagnosed with contact dermatitis syndrome (stage 3A of allergic contact dermatitis syndrome) caused by MUHIα® S2a and MUHIα®EX. Case 2 : A female in her 30s applied Anmeltz® YOKOYOKO, a topical anti-inflammatory and analgesic OTC for stiff shoulders and back pain 6 days prior to presentation. She developed pruritic rash on the neck, left shoulder, and back. Physical examination revealed oval-shaped erythematous lesions on the neck and left shoulder, and brownish patches on the back. As she was patch test-positive to Anmeltz® YOKOYOKO, we diagnosed her with widespread contact dermatitis caused by this medicament. Although OTC medicaments are convenient, patients have to quit using them and consult doctors or pharmacists immediately when they are not effective.</p><p>(日本皮膚免疫アレルギー学会雑誌, 3 (3) : 451-455, 2020)</p>

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