Spontaneous Regression of Sarcoidosis with Panhypopituitarism

  • Kawamata Takaya
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Tanino Yoshinori
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Nikaido Takefumi
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Sato Yuki
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Togawa Ryuichi
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Suzuki Yasuhito
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Watanabe Natsumi
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Saito Mikako
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Rikimaru Mami
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Umeda Takashi
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Koizumi Tatsuhiko
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Hirai Kenichiro
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Uematsu Manabu
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Minemura Hiroyuki
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Fukuhara Atsuro
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Sato Suguru
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Saito Jumpei
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Kanazawa Kenya
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan
  • Hebisawa Akira
    Department of Pathology, Asahi General Hospital, Chiba, Japan
  • Shibata Yoko
    Department of Pulmonary Medicine, Fukushima Medical University, Fukushima, Japan

Bibliographic Information

Other Title
  • 汎下垂体機能低下症を伴い自然軽快したサルコイドーシスの1例
  • 症例報告 汎下垂体機能低下症を伴い自然軽快したサルコイドーシスの1例
  • ショウレイ ホウコク ハンカスイタイ キノウ テイカショウ オ トモナイ シゼン ケイカイ シタ サルコイドーシス ノ 1レイ

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Abstract

<p>症例は,64歳男性.X年Y月中旬から乾性咳嗽と労作時呼吸困難を自覚し,近医を受診した.肺炎として抗菌薬による治 療を受けたが呼吸困難は悪化し,Y+1月初旬に当科を紹介受診した.胸部CT画像で右下葉の浸潤影および周囲の小葉間隔 壁の肥厚,縦隔・両側肺門リンパ節腫大がみられ,FDG-PETでは同部位への集積を指摘された.また,悪性疾患を疑い施 行された頭部MRIでは下垂体の腫大がみられた.確定診断のために行った縦隔リンパ節生検とCTガイド下生検では,非乾 酪性類上皮細胞肉芽腫を認め,可溶性IL-2受容体およびリゾチームの上昇,3系統の下垂体ホルモンの低下を認め,汎下垂 体機能低下症を伴うサルコイドーシスと診断した.入院後,症状および胸部画像所見の改善傾向を認め,無治療で下垂体機 能も含めた臨床所見は改善した.短期間で自然軽快を示した汎下垂体機能低下症を伴うサルコイドーシスを経験したので報 告する.</p>

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