Testing of a dialysis machine used for a patient with coronavirus disease 2019 （COVID‒19） for severe acute respiratory syndrome coronavirus 2 （SARS‒CoV‒2）

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  • Kawajiri Masamori
    Department of Clinical Engineering, The Jikei University School of Medicine
  • Watanabe Takashi
    Department of Clinical Engineering, The Jikei University School of Medicine
  • Inoue Ai
    Department of Clinical Engineering, The Jikei University School of Medicine
  • Iwaya Rieko
    Department of Clinical Engineering, The Jikei University School of Medicine
  • Hiratsuka Akinori
    Department of Clinical Engineering, The Jikei University School of Medicine
  • Hoshina Tokio
    Department of Infectious Diseases, The Jikei University School of Medicine
  • Yamamoto Izumi
    Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine
  • Maruyama Yukio
    Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine
  • Okido Ichiro
    Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine
  • Yokoo Takashi
    Division of Nephrology and Hypertension, Department of Internal Medicine, The Jikei University School of Medicine

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Other Title
  • COVID‒19患者使用後の血液浄化装置におけるRT‒PCRを用いた装置内・外のSARS‒CoV‒2の測定
  • COVID-19患者使用後の血液浄化装置におけるRT-PCRを用いた装置内・外のSARS-CoV-2の測定
  • COVID-19 カンジャ シヨウ ゴ ノ ケツエキ ジョウカ ソウチ ニ オケル RT-PCR オ モチイタ ソウチ ナイ ・ ソト ノ SARS-CoV-2 ノ ソクテイ

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Abstract

<p>Coronavirus disease 2019 （COVID‒19） has become a pandemic, and the number of patients receiving renal replacement therapy （RRT） due to acute kidney injuries （AKI） caused by COVID‒19 has increased. We experienced several cases in which COVID‒19 patients underwent RRT at our institution, and managed to prevent infections from contaminated artificial kidney dialysis machines. When a dialysis machine was used for a COVID‒19 patient, it was not used again for ≥10 days because it was not known how long it takes for the virus to become unviable. Therefore, we were concerned that a shortage of machines for RRT might occur if the number of AKI patients with COVID‒19 continued to increase. To solve this issue, we tested the surfaces, internal fans, and filters of a dialysis machine for severe acute respiratory syndrome coronavirus 2 （SARS‒CoV‒2） using the reverse transcription polymerase chain reaction after a COVID‒19 patient underwent RRT. The results obtained for nine locations, including sites outside and inside of the machine, were all negative. Shortening the time that dialysis machines are kept out of use for after they have been used for COVID‒19 patients requires careful consideration. Further investigations of this issue, involving different environments, are needed. </p>

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