A Case of Human Fascioliasis with Hypereosinophilia and Migrating Liver Abscess

  • NAWATA, Ryohei
    Department of Hematology, Japan Community Healthcare Organization(JCHO)Shimonoseki Medical Center
  • SUGIYAMA Akiko
    Department of Hematology, Japan Community Healthcare Organization(JCHO)Shimonoseki Medical Center
  • KATO Akira
    Department of Gastroenterology and Hepatology, Japan Community Healthcare Organization(JCHO)Shimonoseki Medical Center
  • SETOGUCHI Mihoko
    Department of Diagnostic Pathology, Japan Community Healthcare Organization(JCHO)Shimonoseki Medical Center
  • TAKAHASHI Tetsuro
    Department of Internal Medicine, Saiseikai Toyoura Hospital

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Other Title
  • 好酸球増多と移動性肝膿瘍から肝蛭症と診断した1例
  • コウサンキュウ ゾウタ ト イドウセイ カンノウヨウ カラ カンテツショウ ト シンダン シタ 1レイ
  • 症例報告 好酸球増多と移動性肝膿瘍から肝蛭症と診断した1例
  • ショウレイ ホウコク コウサンキュウ ゾウ タ ト イドウセイ カン ノウヨウ カラ カン ヒルショウ ト シンダン シタ 1レイ

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<p>We experienced a case of human fascioliasis. A 54-year-old female was refered to our hospital with low grade fever and remarkable hypereosinophilia. The laboratory findings included white blood cell 11500/?l with 59% eosinophils and elevated levels hepato-biliary enzyme. Two weeks later, computed tomography demonstrated migrating low-density areas and liver biopsy revealed eosinophilic abscess and granulation. The diagnosis was made by the serological test and eggs in the feces were negative. Treatment with triclabendazole resulted in disappearance of the abnormal liver radiographic findings, and a reduced blood eosinophilic level. This parasitic disease is a neglected infectious disease. We conclude it is necessary to keep in mind that hypereosinophilia and migrating liver abscess are suggestive of human fascioliasis.</p>

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