T<sub>2</sub>-FLAIR Mismatch Sign Is Caused by Long T<sub>1</sub> and T<sub>2</sub> of <i>IDH</i>-mutant, 1p19q Non-codeleted Astrocytoma
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- Kinoshita Manabu
- Department of Neurosurgery, Osaka International Cancer Institute
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- Uchikoshi Masato
- Department of Neurosurgery, Osaka International Cancer Institute Canon Medical Systems Corporation
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- Sakai Mio
- Department of Diagnostic and Interventional Radiology, Osaka International Cancer Institute
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- Kanemura Yonehiro
- Department of Biomedical Research and Innovation, Institute for Clinical Research, National Hospital Organization Osaka National Hospital
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- Kishima Haruhiko
- Department of Neurosurgery, Osaka University Graduate School of Medicine
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- Nakanishi Katsuyuki
- Department of Diagnostic and Interventional Radiology, Osaka International Cancer Institute
Bibliographic Information
- Other Title
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- T2-FLAIR mismatch sign is caused by long T1 and T2 of IDH-mutant, 1p19q Non-codeleted Astrocytoma
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Description
<p>T2-fluid-attenuated inversion recovery images (FLAIR) mismatch sign is now known to be a specific yet insensitive image feature for IDH-mutant, 1p19q non-codeleted astrocytoma. The current study revealed that lesion presenting T2-FLAIR mismatch exhibited extremely long T1- and T2-relaxation time while T2-FLAIR matched lesions showed low to moderate values. On the other hand, IDH-wildtype tumors presented noticeably short T1- and T2-relaxation time. These different relaxation time characteristics seemed to render T2-FLAIR mismatch sign of becoming such a unique and specific image feature for IDH-mutant, 1p19q non-codeleted astrocytoma.</p>
Journal
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- Magnetic Resonance in Medical Sciences
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Magnetic Resonance in Medical Sciences 20 (1), 119-123, 2021
Japanese Society for Magnetic Resonance in Medicine