A Case of HER2-positive Squamous Cell Carcinoma of the Breast

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  • ISHIHARA Hiromasa
    Department of Breast and Endocrine Surgery, Aichi Koseiren Kainan Hospital
  • SHIBATA Arihiro
    Department of Breast and Endocrine Surgery, Aichi Koseiren Kainan Hospital
  • OBATA Yuma
    Department of Breast and Endocrine Surgery, Aichi Koseiren Kainan Hospital
  • ARAKI Takayo
    Department of Breast and Endocrine Surgery, Aichi Koseiren Kainan Hospital
  • TAKASE Tsunenobu
    Department of Breast and Endocrine Surgery, Aichi Koseiren Kainan Hospital
  • YAGUCHI Toyohisa
    Department of Breast and Endocrine Surgery, Aichi Koseiren Kainan Hospital

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Other Title
  • HER2陽性乳腺扁平上皮癌の1例
  • 症例 HER2陽性乳腺扁平上皮癌の1例
  • ショウレイ HER2 ヨウセイ ニュウセン ヘンペイ ジョウヒ ガン ノ 1レイ

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Abstract

<p>A 55-year-old woman with an abnormal finding on screening was referred to our hospital. Ultrasonography revealed a 10 mm irregularly shaped hypoechoic mass in the left breast. The result of aspiration biopsy cytology was positive, and the mass was suspected to be an invasive ductal carcinoma. Computed tomography revealed enlarged axillary lymph nodes, although no distant metastases were observed. We performed total mastectomy of the left breast and axillary lymph node dissection. Pathological findings indicated squamous cell carcinoma of the breast. Immunohistochemical staining revealed that the tumor was negative for estrogen and progesterone receptors, and positive for HER2. On postoperative examination, bone and para-aortic lymph node metastases were observed. The patient died 3 years after surgery. Thus, patients with HER2-positive breast squamous cell carcinoma should be carefully observed.</p>

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