Long-Term Clinical Outcomes of the On-X Mechanical Prosthetic Valve in the Aortic or Mitral Position ― A Single-Center Experience of up to 20 Years’ Follow up ―
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- Kim Ji Seong
- Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital
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- Kang Yoonjin
- Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital
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- Sohn Suk Ho
- Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital
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- Hwang Ho Young
- Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital
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- Choi Jae Woong
- Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital
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- Kim Kyung Hwan
- Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital
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<p>Background:This study evaluated the long-term outcomes for up to 20 years after On-X mechanical valve implantation in the left side of the heart.</p><p>Methods and Results:Between 1999 and 2015, 861 patients (mean age=51.6±10.9 years) who underwent prosthetic valve replacement using the On-X valve in the aortic or mitral position were enrolled (aortic=344, mitral=325, double=192). The mean clinical follow-up duration was 10.5±5.3 (median 10.9) years. Operative mortality occurred in 26 patients (3.0%), and linearized late cardiac mortality was 0.9%/patient-year without an intergroup difference. Linearized thromboembolism, bleeding, prosthetic valve endocarditis, non-structural valve deterioration (NSVD), and reoperation rates were 0.8%/patient-year, 0.6%/patient-year, 0.2%/patient-year, 0.5%/patient-year, and 0.5%/patient-year, respectively. Prosthetic valve endocarditis was more frequent after double valve replacement than after aortic or mitral valve replacement (P=0.008 and 0.005, respectively). NSVD and reoperation rates were significantly lower aortic valve replacement than after mitral or double valve replacement (P=0.001 and 0.002, P=0.001 and <0.001, respectively). Valve replacement in the mitral position was the only risk factor for NSVD (hazard ratio [95% confidence interval]=5.247 [1.608–17.116], P=0.006).</p><p>Conclusions:On-X valve implantation in the left side heart had favorable clinical outcomes with acceptable early and late mortality and a low incidence of prosthetic valve-related complications. Particularly in the aortic position, the On-X valve had better long-term non-structural durability.</p>
収録刊行物
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- Circulation Journal
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Circulation Journal 85 (7), 1042-1049, 2021-06-25
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390007005093943168
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- NII論文ID
- 130008056904
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 031532249
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- PubMed
- 34053969
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可