ブラシノステロイド情報伝達系の化学生物学的研究

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書誌事項

タイトル別名
  • Chemical biology for brassinosteroid signaling
  • 学会賞 ブラシノステロイド情報伝達系の化学生物学的研究
  • ガッカイショウ ブラシノステロイド ジョウホウ デンタツケイ ノ カガク セイブツガクテキ ケンキュウ

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説明

<p>Chemical biology is a new research field to elucidate unknown mysteries in biology by compounds as research tools.　If we are able to find a novel compound that positively regulates plant growth, it will be useful tool, which can elucidate unknown molecular mechanisms in plant growth, and it will be used for applied plant science in agriculture.　Using these chemical biological approaches, I identified novel genes and compounds that regulated plant growth.　In the aspect of gene exploration, I had screened brassinosteroid （BR） signaling genes that promote plant growth.　At first, I had used brassinazole （Brz） that is synthesized as a specific inhibitor for BR biosynthesis enzyme DWF4.　Then, I attempted to screen for a mutant with a Brz-insensitive long hypocotyl phenotype using gain-of-function mutant germinations.　My first isolated mutant was named as bil1 （Brz-inseisitive-long hypocotyl1） and the resulted BIL1 is known as a master transcription factor that regulates 3,000 genes expressions.　Furthermore, I am continuing to screen and analysis of bil mutants, bss（Brz-sensitive-short hypocotyl）, bpg（Brz-insensitive-pale green）mutants.　Trials to reveal molecular mechanisms of plant growth based on novel BR signaling factors are still going on.</p>

収録刊行物

  • 植物の生長調節

    植物の生長調節 55 (1), 1-9, 2020

    一般社団法人 植物化学調節学会

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