Covid-19, Mutations, Immune Responses and Vaccines

DOI

Bibliographic Information

Other Title
  • 新型コロナウィルスの変異・免疫・ワクチン

Abstract

<p>The new coronavirus mutates about 24 out of the 30,000 base sequences in one year. It is a relatively stable RNA virus. Viruses with new mutations are selected about every three months, and the number of infected people rises, then decrease due to self-destruction may happen, drawing a wave.</p><p>As a mechanism to create this periodicity, selections are mediated by multi-scale of interactions such as molecular level, host immunity, social isolation and treatment, and zoonotic infections with animals. The pandemic is expected to end in the next few years.</p><p>The problem is that with each wave, the number of carriers of a virus called basic clade, which has a relatively stable origin, increases at the epicenter, and mutant strains are produced from there. Of particular concern is the increase in vaccine-resistant viruses that reduce susceptibility and causes prolonged pandemic.</p><p>I would like to consider a countermeasure to end the coronavirus pandemic from the view point of the mechanism generating periodicity.</p>

Journal

Details 詳細情報について

  • CRID
    1390007536267632128
  • NII Article ID
    130008073574
  • DOI
    10.14869/toxpt.48.1.0_el7
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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