Covid-19, Mutations, Immune Responses and Vaccines
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- KODAMA Tatsuhiko
- RCAST, University of Tokyo
Bibliographic Information
- Other Title
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- 新型コロナウィルスの変異・免疫・ワクチン
Abstract
<p>The new coronavirus mutates about 24 out of the 30,000 base sequences in one year. It is a relatively stable RNA virus. Viruses with new mutations are selected about every three months, and the number of infected people rises, then decrease due to self-destruction may happen, drawing a wave.</p><p>As a mechanism to create this periodicity, selections are mediated by multi-scale of interactions such as molecular level, host immunity, social isolation and treatment, and zoonotic infections with animals. The pandemic is expected to end in the next few years.</p><p>The problem is that with each wave, the number of carriers of a virus called basic clade, which has a relatively stable origin, increases at the epicenter, and mutant strains are produced from there. Of particular concern is the increase in vaccine-resistant viruses that reduce susceptibility and causes prolonged pandemic.</p><p>I would like to consider a countermeasure to end the coronavirus pandemic from the view point of the mechanism generating periodicity.</p>
Journal
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- Annual Meeting of the Japanese Society of Toxicology
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Annual Meeting of the Japanese Society of Toxicology 48.1 (0), EL7-, 2021
The Japanese Society of Toxicology
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Details 詳細情報について
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- CRID
- 1390007536267632128
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- NII Article ID
- 130008073574
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed