Myocardial infarction model in severe combined immunodeficiency mice

DOI

Bibliographic Information

Other Title
  • 重度免疫不全マウスを用いた心筋梗塞モデル作製

Description

<p>We compared two myocardial infarction models of C57BL/6J and NOD/ShiJic-ScidJcl-mice. Infarction was induced by complete ischemia of the left anterior descending artery. Cardiac function was measured by echocardiography. Infarct size was measured in Masson’s trichrome-stained specimens. In both mouse strains, EF and %FS decreased from day 1 (the first day of model preparation). EF, %FS, LVIDd, and LVIDs remained similar to those on day 7 until day 28. Myocardial fibrosis area ratios were almost equal. No differences were observed between the two mouse strains.</p>

Journal

Details 詳細情報について

  • CRID
    1390007536268925824
  • NII Article ID
    130008073668
  • DOI
    10.14869/toxpt.48.1.0_p-169
  • Text Lang
    ja
  • Data Source
    • JaLC
    • CiNii Articles
  • Abstract License Flag
    Disallowed

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