A Case Report of Paneth Cell Carcinoma in the Stomach
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- Tatsumi Yoshiaki
- Department of General Surgery, Hyogo Brain and Heart Center at Himeji
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- Sakai Tetsuya
- Department of Surgery, Steel Memorial Hirohata Hospital
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- Ito Takashi
- Department of Pathology, Steel Memorial Hirohata Hospital
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- Ami Katsuya
- Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Kobe University Graduate School of Medicine
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- Tanaka Masaki
- Department of Surgery, Steel Memorial Hirohata Hospital
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- Morimoto Haruki
- Department of Surgery, Steel Memorial Hirohata Hospital
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- Takenaga Masanori
- Department of Surgery, Inami Central Hospital
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- Iwatani Yoshiteru
- Department of Surgery, Steel Memorial Hirohata Hospital
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- Fukuoka Masato
- Department of Surgery, Steel Memorial Hirohata Hospital
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- Tachibana Shiro
- Department of Surgery, Steel Memorial Hirohata Hospital
Bibliographic Information
- Other Title
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- パネート細胞胃癌の1例
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Abstract
<p>A 76-year-old woman was referred to our hospital for complaints of nausea, loss of appetite, and an upper abdominal mass,. Initially, she was diagnosed with multiple gastric ulcers with Helicobacter pylori infection by upper gastrointestinal endoscopy, and medication was administered. However, reexamination by endoscopy after this treatment revealed type 4 advanced gastric cancer, special type (miscellaneous carcinoma). Additional tests, including immunostaining with anti-lysozyme antibody (lysozyme staining), revealed Paneth cell gastric cancer (World Health Organization classification) and distal gastrectomy was performed. Twenty-two months after the operation, there was no obvious recurrence. Paneth cells are found in gastric mucosa as a result of intestinal metaplasia. Several studies have reported that Paneth cell-like cells containing positive granules that stain with lysozyme are found in gastric cancer tissue during the process of carcinogenesis. However, Paneth cell gastric cancer, in which small tumor cells containing granules in the cytoplasm infiltrate diffusely, as in the present case, is extremely rare.</p>
Journal
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- The Japanese Journal of Gastroenterological Surgery
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The Japanese Journal of Gastroenterological Surgery 54 (8), 514-522, 2021-08-01
The Japanese Society of Gastroenterological Surgery
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Keywords
Details 詳細情報について
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- CRID
- 1390007750043577216
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- NII Article ID
- 130008080866
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- ISSN
- 13489372
- 03869768
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- Text Lang
- ja
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- Data Source
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- JaLC
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed