Improvement of Standardized Uptake Value Accuracy in the <sup>99m</sup>Tc Body SPECT and SPECT/CT: Optimization of the Phantom for Calculating Becquerel Calibration Factor and Correction Method

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  • Nakamura Yuto
    Department of Radiological Technology, Yamaguchi University Hospital
  • Kangai Yoshiharu
    Department of Radiological Technology, Yamaguchi University Hospital
  • Abe Toshinori
    Department of Radiological Technology, Kawasaki Medical School Hospital
  • Nakahara Yuki
    Department of Radiological Technology, Yamaguchi University Hospital

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Other Title
  • <sup>99m</sup>Tc を使用した体幹部 SPECT および SPECT/CT における SUV 精度向上のための評価 ： BCF 算出ファントムと画像再構成時の補正法の最適化
  • [99m]Tcを使用した体幹部SPECTおよびSPECT/CT におけるSUV精度向上のための評価 : BCF算出ファントムと画像再構成時の補正法の最適化
  • [99m]Tc オ シヨウ シタ タイカンブ SPECT オヨビ SPECT/CT ニ オケル SUV セイド コウジョウ ノ タメ ノ ヒョウカ : BCF サンシュツ ファントム ト ガゾウ サイコウセイジ ノ ホセイホウ ノ サイテキカ

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Abstract

<p>Purpose: The purpose of this study was to evaluate the best phantom for calculating the becquerel calibration factor (BCF) and correction method to obtain the improvement of standardized uptake value (SUV) accuracy in both single photon emission computed tomography (SPECT) and SPECT/CT. Method: A SPECT/CT scanner was used in this study. BCFs were calculated using four phantoms with different cross sections including National Electrical Manufacturers Association International Electrotechnical Commission body phantom (NEMA IEC body phantom) filled with 99mTcO4-, and five correction methods were used for reconstruction. SUVs were calculated by the NEMA IEC body phantom and pediatric phantom in house with these BCFs. We then measured SUVmean in the background region of the NEMA IEC body phantom, SUVmax and SUVpeak of the 37-mm-diameter sphere. Results: In the SPECT scanner, SUVmean and SUVmax measured 1.04 and 4.02, respectively, in the case of BCF calculation and SUV measurement using NEMA IEC body phantoms without corrections. In the SPECT/CT scanner, SUVmean with CT attenuation correction (AC) was in agreement with the theoretical values using each phantom. SUVmax showed the same trend. Conclusion: In the SPECT scanner, it is possible to obtain a highly accurate SUV by using a phantom that matches the size of the subject for BCF calculation and without correction. In the SPECT/CT scanner, highly accurate SUVs can be obtained by using CT-based attenuation correction, and these values do not depend on the size of the BCF calculation phantom.</p>

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