Aural stimulation with capsaicin prevented pneumonia in dementia patients

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  • Jinnouchi Osamu
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences Department of Otolaryngology, Anan Kyoei Hospital
  • Ohnishi Hiroki
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences
  • Kondo Eiji
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences
  • Kawata Ikuji
    Department of Otolaryngology, Anan Kyoei Hospital
  • Bando Hiroyasu
    Department of Respiratory Medicine, Tokushima Prefectural Kaifu Hospital
  • Okamoto Hidehiko
    Department of Physiology, International University of Health and Welfare School of Medicine
  • Azuma Takahiro
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences
  • Sato Go
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences
  • Kitamura Yoshiaki
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences
  • Abe Koji
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences
  • Takeda Noriaki
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences

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Other Title
  • カプサイシン軟膏による外耳道刺激は高齢認知症患者の肺炎を予防する

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In the present study, we examined the effects of daily application of capsaicin ointment to the external auditory canal for 6 months on the development of pneumonia in elderly dementia patients at high risk of aspiration.Twenty-nine oldest-old bedridden dementia inpatients at high risk of aspiration were enrolled in the present study. Ointment containing 0.025% capsaicin was applied to each external auditory canal with a cotton swab alternatively once a day for 6 months.The incidence of pneumonia during the 6 months before the intervention was 1.80±0.37 in these patients. However, this incidence significantly decreased to 0.40±0.29 (p0.01) during the 6 months of the alternative application of capsaicin ointment to each auditory canal. No adverse effect such as otalgia was observed.These findings suggest that daily long-term aural stimulation with capsaicin ointment enhanced the cough reflex via Arnold's ear-cough reflex as a glottis protective measure, resulting in the reduction of incidence of pneumonia in elderly dementia patients at high risk of aspiration. The daily aural stimulation with capsaicin ointment may be a safe and promising intervention to prevent aspiration pneumonia in elderly people, especially those who cannot undergo swallowing exercise.

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