カプサイシン軟膏による外耳道刺激は高齢認知症患者の肺炎を予防する

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  • 陣内 自治
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences Department of Otolaryngology, Anan Kyoei Hospital
  • 大西 皓貴
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences
  • 近藤 英司
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences
  • 川田 育二
    Department of Otolaryngology, Anan Kyoei Hospital
  • 坂東 弘康
    Department of Respiratory Medicine, Tokushima Prefectural Kaifu Hospital
  • 岡本 秀彦
    Department of Physiology, International University of Health and Welfare School of Medicine
  • 東 貴弘
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences
  • 佐藤 豪
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences
  • 北村 嘉章
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences
  • 阿部 晃治
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences
  • 武田 憲昭
    Department of Otolaryngology, Tokushima University Graduate School of Biomedical Sciences

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  • Aural stimulation with capsaicin prevented pneumonia in dementia patients

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In the present study, we examined the effects of daily application of capsaicin ointment to the external auditory canal for 6 months on the development of pneumonia in elderly dementia patients at high risk of aspiration.Twenty-nine oldest-old bedridden dementia inpatients at high risk of aspiration were enrolled in the present study. Ointment containing 0.025% capsaicin was applied to each external auditory canal with a cotton swab alternatively once a day for 6 months.The incidence of pneumonia during the 6 months before the intervention was 1.80±0.37 in these patients. However, this incidence significantly decreased to 0.40±0.29 (p0.01) during the 6 months of the alternative application of capsaicin ointment to each auditory canal. No adverse effect such as otalgia was observed.These findings suggest that daily long-term aural stimulation with capsaicin ointment enhanced the cough reflex via Arnold's ear-cough reflex as a glottis protective measure, resulting in the reduction of incidence of pneumonia in elderly dementia patients at high risk of aspiration. The daily aural stimulation with capsaicin ointment may be a safe and promising intervention to prevent aspiration pneumonia in elderly people, especially those who cannot undergo swallowing exercise.

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