A CASE OF PANCAKE SYNDROME IN WHICH MITES COULD BE DETECTED FROM COOKED TAKOYAKI

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  • Ishiguro Tomonori
    Department of Allergy, Allergy and Immunology Center, Aichi Children's Health and Medical Center
  • Matsui Teruaki
    Department of Allergy, Allergy and Immunology Center, Aichi Children's Health and Medical Center
  • Matsumoto Keiji
    Nikkaku Laboratory Co., Ltd.
  • Watanabe Yukari
    Department of Pediatrics, Okazaki City Hospital
  • Hamashima Hiroshi
    Department of Clinical Laboratory, Aichi Children's Health and Medical Center
  • Ikeyama Takanari
    Division of Pediatric Critical Care Medicine, Aichi Children's Health and Medical Center
  • Kubota Shouhei
    Department of Allergy, Allergy and Immunology Center, Aichi Children's Health and Medical Center
  • Kitamura Katsumasa
    Department of Allergy, Allergy and Immunology Center, Aichi Children's Health and Medical Center
  • Takasato Yoshihiro
    Department of Allergy, Allergy and Immunology Center, Aichi Children's Health and Medical Center
  • Sugiura Shiro
    Department of Allergy, Allergy and Immunology Center, Aichi Children's Health and Medical Center
  • Ito Komei
    Department of Allergy, Allergy and Immunology Center, Aichi Children's Health and Medical Center

Bibliographic Information

Other Title
  • 調理後のたこ焼きからダニを検出できたパンケーキ症候群の1例
  • チョウリ ゴ ノ タコヤキ カラ ダニ オ ケンシュツ デキタ パンケーキ ショウコウグン ノ 1レイ

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<p>A 12-year-old girl experienced anaphylactic shock and respiratory failure immediately after eating 4 pieces of takoyaki made at home. We suspected pancake syndrome because of the three reasons: First, the patient had a history of bronchial asthma and allergic rhinitis without any history of food allergies; Second, takoyaki flour that had been stored at room temperature for one month after opening the package had been used; and Third, both the specific IgE (ImmunoCAP® method) of Dermatophagoides farinae and Dermatophagoides pteronyssinus were found to be above the detection limit. Since the suspected flour had been discarded, a specimen of tako yaki was examined microscopically and 430 mites/g were identified. Although only 21.1ng/g of Der f 1 was detected by an ELISA, this amount was less than expected, based on the number of mites that had been observed. The decrease in the antigenicity of mite allergens due to heating and reducing agents, and the insolubilization of mite allergens due to disulfide bonds between the mite allergens and gluten were thought have made it difficult to identify mite antigens by ELISA.</p><p>When pancake syndrome is suspected, and the flour that is thought to have caused the condition is difficult to obtain, microscopic identification of mites in cooked food should be considered.</p>

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