Effects of Poultice Application to Skin Lesions Induced by Extravasation of Administered Catecholamines: An Experimental Study

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  • カテコラミン製剤の漏出性皮膚傷害に対する罨法の効果に関する基礎研究
  • カテコラミン セイザイ ノ ロウシュツセイ ヒフ ショウガイ ニ タイスル アンポウ ノ コウカ ニ カンスル キソ ケンキュウ

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<p>Purpose: The present study was to develop an evidence-based nursing procedure for skin lesions induced by subcutaneous injection of catecholamines using an extravasation rat model.</p><p>Methods: Skin lesions were induced in rats by subcutaneous injection of catecholamines into the back skin, and then the effects of applying a poultice were observed.</p><p>Results: In a control group for which no poultice was applied, flare-up was observed in three rats on the first day, and in one of these rats an ulcer developed on the third day. In a group treated with a hot poultice, flare-up was observed in five rats on the first day, and all of those rats developed ulcers on the third day. On the other hand, no skin lesions occurred in a group treated with a cold poultice.</p><p>Conclusion: When extravasation of catecholamines occurs, application of a hot poultice for vasodilation causes deterioration of the skin lesions whereas a cold poultice for suppression of inflammation is effective for prevention of skin lesions.</p>

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