書誌事項
- タイトル別名
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- Efficacy and risk of intravenous rt-PA therapy for mild or rapidly improving ischemic stroke
- NIHSS4テン イカ ノ ケイショウ マタワ ショウジョウ ノ キュウソク カイゼン オ シメス ノウコウソク ニ タイスル ジョウチュウ ケッセン ヨウカイ(rt-PA)リョウホウ ノ ユウコウセイ オヨビ キケンセイ ノ ケントウ
この論文をさがす
説明
<p>Purpose: We aimed to evaluate the efficacy and risk of intravenous recombinant tissue plasminogen activator (rtPA) thrombolysis in patients with mild or rapidly improving ischemic stroke.</p><p>Methods: We retrospectively examined 143 ischemic stroke patients who underwent intravenous rt-PA therapy in our stroke center from December 2009 to August 2019. Mild stroke was defined as National Institute of Health Stroke Scale (NIHSS) score ≤4. Rapidly improving stroke was defined as a ≥4-point NIHSS score improvement from the time of initial evaluation to the time of thrombolysis decision. Patients with mild or rapidly improving stroke (Group A) were compared with patients with other stroke (Group B). Subanalysis of Group A further compared stable mild stroke (Group A-1) with rapidly improving stroke (Group A-2) and stroke rapidly improving to mild severity (Group A-3).</p><p>Results: No hemorrhagic complication occurred in Group A. At discharge, 90.7% of Group A patients exhibited a modified Rankin scale score ≤2. rt-PA was more effective in Groups A-2 and A-3 than Group A-1.</p><p>Conclusions: Intravenous rt-PA treatment should be considered in patients with mild or rapidly improving ischemic stroke. </p>
収録刊行物
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- Journal of Japan Society of Neurological Emergencies & Critical Care
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Journal of Japan Society of Neurological Emergencies & Critical Care 33 (2), 16-22, 2021-12-01
一般社団法人 日本神経救急学会
