A Review on the Foodomics Based on Liquid Chromatography Mass Spectrometry

  • Muguruma Yoshio
    Graduate School of Pharmaceutical Sciences, Ritsumeikan University
  • Nunome Mari
    Graduate School of Pharmaceutical Sciences, Ritsumeikan University
  • Inoue Koichi
    Graduate School of Pharmaceutical Sciences, Ritsumeikan University

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Abstract

<p>Due to the globalization of food production and distribution, the food chain has become increasingly complex, making it more difficult to evaluate unexpected food changes. Therefore, establishing sensitive, robust, and cost-effective analytical platforms to efficiently extract and analyze the food-chemicals in complex food matrices is essential, however, challenging. LC/MS-based metabolomics is the key to obtain a broad overview of human metabolism and understand novel food science. Various metabolomics approaches (e.g., targeted and/or untargeted) and sample preparation techniques in food analysis have their own advantages and limitations. Selecting an analytical platform that matches the characteristics of the analytes is important for food analysis. This review highlighted the recent trends and applications of metabolomics based on “foodomics” by LC-MS and provides the perspectives and insights into the methodology and various sample preparation techniques in food analysis.</p>

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