Systematic review of magnetic resonance imaging in corticosteroid-associated osteonecrosis of the femoral head: 30 yearsof advances

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  • ステロイド性大腿骨頭壊死症のMRIに関するシステマティックリビュー -30年の進歩-

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Magnetic Resonance Imaging (MRI) was first utilized for the diagnosis of osteonecrosis in 1983. The purpose of this current study is to review the past 30 years of achievement using new developments in MRI technology for investigation into the pathogenesis of osteonecrosis of the femoral head associated with corticosteroid therapy. From 1983 to 2013, 165 MRI studies were reported: 25 articles in 1983-1993, 55 in 1994-2003, and 85 in 2004-2013. Forty-nine articles were reported from Japan, 44 from the United States, and 18 from China. Eighty-two studies were retrospective, 49 were prospective, 20 were case reports, two were genotyping studies, and 10 used animal models. MRI is a promising tool for monitoring osteonecrosis and analyzing the pathogenesis in both clinical and experimental studies.

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