Prevalence and Risk Factors for Diabetes: A Ten Year Follow-up Study of the Yaeyama District of Okinawa

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  • Okada Kyoko
    Department of General Medicine, Kyushu University Hospital
  • Furusyo Norihiro
    Department of Environmental Medicine and Infectious Diseases, Faculty of Medical Sciences, Kyushu University | Department of General Medicine, Kyushu University Hospital
  • Sawayama Yasunori
    Department of General Medicine, Kyushu University Hospital
  • Kanamoto Yoko
    Department of General Medicine, Kyushu University Hospital
  • Murata Masayuki
    Department of General Medicine, Kyushu University Hospital
  • Hayashi Jun
    Department of Environmental Medicine and Infectious Diseases, Faculty of Medical Sciences, Kyushu University | Department of General Medicine, Kyushu University Hospital

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Other Title
  • 10年間の追跡調査による沖縄県八重山地区における糖尿病有病率と罹患率及びその危険因子についての検討

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Abstract

To clarify the prevalence and incidence of diabetes and to evaluate which risk factors are predictive of future diabetes in the general population of Okinawa, 1,690 residents were screened in 1989 and 758 were prospectively followed-up in 1999. Of the 1,690 residents surveyed in 1989 and 1, 163 in1999, diabetes was found in 91 (5.4%) in1989 and 52 (4.5%) in 1999. Residents with diabetes were significantly older, more likely to have significantly higher levels of HbA1c, fasting glucose, serum triglyceride, ALT, BMI, systolic blood pressure, and a history of hypertension than non diabetic residents, both in 1989 and 1999. 717 residents who did not have diabetes at the 1989 screening were re-examined in 1999. Among them, 17 (incidence rate 2.4%) had developed diabetes over the ten years. Multivariate logistic regression analysis showed HbA1c, BMI, and systolic blood pressure to be independent risk factors for newly developed diabetes (p < 0.0001, odds ratio ; 28.1, p = 0.020, odds ratio ; 1.21, p = 0.039, odds ratio ; 1.04, respectively) after adjusting for age, sex, BMI, blood pressure, hystory of hypertension, HbA1c, fasting glucose, serum triglyceride, ALT, and γ GTP. Our results showed that the prevalence and incidence of diabetes are low in the general population of the Yaeyama district of Okinawa and that elevated HbA1c level, even in the normal range, is one of the best predictors of diabetes. Following BMI and systolic blood pressure is important.

Journal

  • 福岡醫學雜誌

    福岡醫學雜誌 101 (10), 215-224, 2010-10-25

    Fukuoka Medical Association

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