ストレプトマイシンによる膀胱結核の治験

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A report on 42 cases of tuberculos cystitis treated with streptomysin as compared to 21 cases not receiving any chemical treatment. Out of the 42 cases 36 had renal tuberculosis of unilateral kidney (the other kidney had been removed; and 6 had tuberculosis of bilateral kidney. A total of 5 to 30 g was administered in doses varying from 0.5 to 1.0 g daily. The effects were observed through vesical symptoms : burning and frequent urination, urinary findings, cystoscopic findings and vesical capacity. Out of the 42, 20 showed remarkable improvement, 14 fair, 6 some and 2 none. The improvements were out standing in burning urination; out of the 42 cases symptoms completely vanished from 20 and 15 improved strikingly. Against frequent urination, obvious improvements were also observed which however were not as remarkable as in the cases of burning urination. Cystoscopically in 9 cases ulcers completely disappeared and in 20 ulcers were reduced remarkably. The slighter the lesions were the more conspicuous the improvements. It is worthy of notice that in one serious cases in which 20 g of streptomycin was administered, contracture of the bladder and stricture of the urethra resulted. III effects were observed in 6 cases out of the 42 which however disappeared shortly 'after termination of injections.

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