The B Complex in the Chicken : Development from a blood group system into the major histocompatibility complex <Review>

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  • 鶏におけるB複合体 : 血液型システムから主要組織適合複合体への発展
  • 鶏におけるB複合体--血液型システムから主要組織適合複合体への発展〔英文〕
  • ニワトリ ニ オケル B フクゴウタイ ケツエキガタ システム カラ シュヨウ

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Abstract

The major histocompatibility complex (MHC) in chickens was initially described as a blood group locus called the B system. Early studies on the B blood group system re-vealed that the B system was associated with some physiological functions. Subsequently, it was found that the B system was associated with several immunological functions and should be the MHC in chickens.Then, the system is now called the B complex. The B complex is composed of three regions, B-G, B-F and B-L, and regulates a number of functions similar to those found in mammalian MHC. The DNA structure of each region within the B complex is now gradually becoming clear.

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