A CASE OF MINIMALLY INVASIVE ENDOSCOPIC RESECTION OF A THYROID-LIKE LOW GRADE NASOPHARYNGEAL PAPILLARY ADENOCARCINOMA BY THE TRANSNASAL APPROACH

DOI
  • Harayama Yukihisa
    Department of Otorhinolaryngology, The Jikei University School of Medicine Department of Otorhinolaryngology-Head and Neck Surgery The Jikei University Katsushika Medical Center
  • Iida Makoto
    Department of Otorhinolaryngology-Head and Neck Surgery The Jikei University Katsushika Medical Center
  • Nishiya Yukio
    Department of Otorhinolaryngology, The Jikei University School of Medicine
  • Kessoku Hisashi
    Department of Otorhinolaryngology, The Jikei University School of Medicine
  • Shimura Eiji
    Department of Otorhinolaryngology, The Jikei University School of Medicine

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Other Title
  • Thyroid-like low grade nasopharyngeal papillary adenocarcinoma を経鼻的内視鏡下に切除し得た1例

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Abstract

<p>　Thyroid-like low-grade nasopharyngeal papillary adenocarcinoma is an extremely rare malignant tumor of nasopharyngeal mucosal epithelial origin. Histopathologically, it is an adenocarcinoma characterized by abnormal expression of thyroid transcription factors and papillary thyroid carcinoma-like morphology, but resembles a squamous cell carcinoma. There has been only one reported case domestically, while 24 cases have been reported from overseas. These reports mainly describe the histopathological findings and clinical progression of the cases, with scarce reference to the treatment strategies. Although the tumor is a low-grade carcinoma, the number of reported cases is extremely small, and no standard treatment has been established ; therefore, it remains unclear if it can be treated using the same treatment strategy as that adopted for the more common squamous cell carcinoma. We considered that this rare low-grade tumor could be resected in a minimally invasive manner by transnasal endoscopic surgery, even though the resection margins might be narrow. Herein, we report the resection plan and the procedure.</p>

Journal

  • JIBI INKOKA TEMBO

    JIBI INKOKA TEMBO 64 (1), 43-49, 2021-02-15

    Society of Oto-rhino-laryngology Tokyo

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