魚類初期生活段階毒性試験の海産魚モデルとしてのクサフグの利用可能性について

仲山 慶, 池田 踏青, 黒川 大輔, 北條 裕也, 宇野 誠一

doi:10.11403/jset.25.1

書誌事項

タイトル別名

Use of pufferfish, <i>Takifugu niphobles</i>, for early-life stage toxicity test as a marine fish model

説明

<p>The present study tested the early life stage toxicity of 3,5-dichlorophenol (3,5-DCP) on grass puffer, Takifugu niphobles, in order to evaluate its potential use as a marine fish model. The pufferfish embryos at 1-day post fertilization (dpf) were exposed to serially diluted 3,5-DCP at 20°C or 25°C until 14- or 10-dpf, respectively. Exposure to 3,5-DCP caused inhibition of pigmentation, of swimming, and of yolk absorption. The EC₅₀ of morphological abnormality and the LC₅₀ at the end of test were 0.97 and 1.4 mg/L at 25°C. The EC₅₀ and LC₅₀ values estimated at 20°C (0.75 and 0.79 mg/L, respectively) were generally similar to those at 25°C. The sensitivity to 3,5-DCP in the grass puffer was equivalent to those observed in other marine fish species. Because of the ease of handling and observation of embryos, and the high hatching and survival rates, we consider the grass puffer to be an ideal model for early-life stage toxicity testing.</p>

収録刊行物

環境毒性学会誌

環境毒性学会誌 25 (0), 1-9, 2022-02-22

日本環境毒性学会

キーワード

詳細情報詳細情報について

CRID: 1390009683030942720

NII論文ID: 130008162619

DOI: 10.11403/jset.25.1

ISSN: 18825958; 13440667

本文言語コード: ja

データソース種別

JaLC
CiNii Articles

抄録ライセンスフラグ: 使用不可

書き出し

問題の指摘