Whole-body MRI with Diffusion-weighted Imaging for the Detection of Metastases after Surgical Resection for Breast Cancer

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  • Osanai Takayuki
    Department of Surgery, Tokyo Metropolitan Health and Medical Treatment Corporation, Ohkubo hospital
  • Uehira Daisuke
    Department of Surgery, Tokyo Metropolitan Health and Medical Treatment Corporation, Ohkubo hospital
  • Murakata Ayano
    Department of Surgery, Tokyo Metropolitan Health and Medical Treatment Corporation, Ohkubo hospital
  • Yatabe Yusuke
    Department of Surgery, Tokyo Metropolitan Health and Medical Treatment Corporation, Ohkubo hospital
  • Tanami Hideaki
    Department of Surgery, Tokyo Metropolitan Health and Medical Treatment Corporation, Ohkubo hospital

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  • 乳癌術後全身検索における非造影拡散強調画像併用全身核磁気共鳴画像に関する検討

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Abstract

<p>We examined the usefulness of diffusion-weighted imaging of the whole body with background body signal suppression (DWIBS) for non-contrast diffusion-weighted imaging for the diagnosis of bone metastases and also for the diagnosis of metastasis to other visceral organs in patients with breast cancer treated by surgery. Bone scintigraphy (BS) and whole-body magnetic resonance imaging (MRI) (1.5 tesla) were performed in 60 breast cancer patients after surgery, and DWIBS-based fat suppression combined with DWI and heavy T2-weighted imaging using a balanced SSFP sequence were used. Cross-sectional images were taken from the parietal region to the pelvis in 30 slices in four areas. Furthermore, the whole spinal cord scanning in sagittal sections by fast spin echo T1-weighted imaging was imaged in two slices with 29 slices. DWIBS showed 100% sensitivity and 96.6% specificity as compared to BS. Metastasis to the visceral organs was suspected in 3 cases by DWIBS, but closer examination revealed a negative result. DWIBS seems to be a useful test method for detecting bone metastasis in breast cancer patients after surgical treatment.</p>

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