A favorable clinical course of acute myeloid leukemia with t (6;21;8)(p23;q22;q22)
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- WADA Atsushi
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- DOKI Noriko
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- OTSUKA Yuki
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- ADACHI Hiroto
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- KONUMA Ryosuke
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- KISHIDA Yuya
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- KONISHI Tatsuya
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- YAMADA Yuta
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- NAGATA Akihito
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- NAGATA Ryohei
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- MARUMO Atsushi
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- NOGUCHI Yuma
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- MUKAE Junichi
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- TOYA Takashi
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- IGARASHI Aiko
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- NAJIMA Yuho
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- KOBAYASHI Takeshi
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- HARADA Hironori
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital Laboratory of Oncology, School of Life Sciences, Tokyo University of Pharmacy and Life Sciences
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- HARADA Yuka
- Clinical Research Support Center, Tokyo Metropolitan Cancer, and Infectious diseases Center Komagome Hospital
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- SAKAMAKI Hisashi
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
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- OHASHI Kazuteru
- Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital
Bibliographic Information
- Other Title
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- 良好な経過を辿ったt(6;21;8)(p23;q22;q22)を有する急性骨髄性白血病
- リョウコウ ナ ケイカ オ タドッタ t(6;21;8)(p23;q22;q22)オ ユウスル キュウセイ コツズイセイ ハッケツビョウ
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Description
<p>Variants of the t (8;21) (q22;q22) involving chromosome 8, 21, and other chromosomes account for about 3% of all t (8;21) (q22;q22) in patients with acute myeloid leukemia (AML). However, the prognosis of AML with variant t (8;21) remains unknown due to the scarcity of reported cases. Herein we report a case of AML with t (6;21;8) (p23;q22;q22). Fluorescence in situ hybridization confirmed a RUNX1-RUNX1T1 fusion signal on the derivative chromosome 8. This is the first report on a variant of t (8;21) involving the breakpoint 6p23. After induction chemotherapy, our patient achieved complete remission and has been stable for four years.</p>
Journal
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- Rinsho Ketsueki
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Rinsho Ketsueki 63 (2), 104-107, 2022
The Japanese Society of Hematology
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Details 詳細情報について
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- CRID
- 1390010292560717056
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- NII Book ID
- AN00252940
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- ISSN
- 18820824
- 04851439
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- NDL BIB ID
- 032023655
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- PubMed
- 35264498
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- Text Lang
- ja
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- Article Type
- journal article
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- Data Source
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- JaLC
- NDL Search
- KAKEN
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- Abstract License Flag
- Disallowed